Cd180 antibody
WebThe G28-8 monoclonal antibody specifically recognizes RP105/Bgp95, a 95-105 kDa type I membrane protein consisting of extracellular leucine-rich repeats and a short … WebCD180 is a type 1 membrane protein consisting of extracellular leucinerich repeats (LRR) and a short cytoplasmic tail. It regulates B cell recognition of …
Cd180 antibody
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WebThe monoclonal antibody MHR73-11 recognizes human CD180, also known as RP105, which is a 105 kDa type 1 transmembrane protein of the toll-like receptor (TLR) … WebCD180 consists of extracellular leucine-rich repeats (LRR) and a short cytoplasmic tail. The extracellular LRR is part of the cell surface …
WebCD180. CD180 antigen [radioprotective 105kDa protein (RP105)] was identified as a leucine-rich repeat (LRR) protein expressed on the surface of B cells [77]. From: … WebAdditionally, MD-1, a secretory protein, associates with CD180 (RP105) at the cell surface and this complex, in conjunction with TLR4, recognizes bacterial LPS. The human CD180 (RP105) gene maps to 5q12. The MHR73-11 antibody is able to activate B cells and to protect against irradiation- or dexamethasone-induced apoptosis. Product Details
WebThe RP/14 monoclonal antibody specifically binds to CD180, the "radioprotective" 105 kDa (RP105) antigen expressed on mature B lymphocytes. Like other members of the Toll-like Receptor (TLR) family, the extracellular region of CD180 contains tandem repeats of a leucine-rich motif flanked by regions containing conserved cysteines. WebProduct Specific Information Description: The MHR73-11 monoclonal antibody reacts with human CD180 (RP105). This 105 kDa type I transmembrane molecule is a member of the TLR family of proteins characterized by an extracellular domain with leucine-rich repeats and a cytoplasmic domain with homology to the type I IL-1 receptor.
WebSep 9, 2013 · In this study, we investigated the effect of targeting Ags to a receptor expressed on both DCs and B cells. We selected the 95-kD B cell–associated surface molecule CD180 (also called Bgp95 or RP105) as a target because (a) ligating CD180 with mAb triggers B cell activation and proliferation (Valentine et al., 1988; Miyake et al., …
WebThe mouse monoclonal antibody G28-8 recognizes an extracellular epitope of RP105/CD180, a 95-105 kDa TLR-like glycoprotein expressed on peripheral blood monocytes and dendritic cells, mantle zone B cells and marginal zone B cells, but very weakly on germinal center B cells. Isotype. IgG1 Kappa. Clonality. tach-it 3570WebCD180 Antibodies CD180 ELISA Kits CD180 Proteins CD180 Peptides CD180 is a cell surface molecule consisting of extracellular leucine-rich repeats (LRR) and a short cytoplasmic tail. The extracellular LRR is associated with a molecule called MD-1 and form the cell surface receptor complex, RP105/MD-1. It belongs to the family of pathogen ... tach-it 3567 semi-automatic twist tie machineWebLigation of CD180 by monoclonal antibodies leads to B cell activation, upregulation of CD80/CD86, and increase in cell size. CD180 consists of extracellular leucine-rich repeats (LRR) and a short cytoplasmic tail. The extracellular LRR is part of the cell surface receptor complex, RP105/MD-1. Diseases associated with CD180 dysfunction include ... tach-it e-9 bag sealerWebThis CD180 antibody is conjugated to Biotin. Application. All applications for CD180 antibodies. Flow Cytometry (FACS) Brand. BD Pharmingen™. Characteristics. The … tach-it bl-1WebLigation of CD180 by monoclonal antibodies leads to B cell activation, upregulation of CD80/CD86, and increase in cell size. CD180 consists of extracellular leucine-rich repeats (LRR) and a short cytoplasmic tail. The extracellular LRR is part of the cell surface receptor complex, RP105/MD-1. Diseases associated with CD180 dysfunction include ... tach-it heavy duty tape gunWebThe G28-8 monoclonal antibody specifically recognizes RP105/Bgp95, a 95-105 kDa type I membrane protein consisting of extracellular leucine-rich repeats and a short cytoplasmic domain. It is expressed on mantle zone B cells, but weakly on germinal center B cells. RP105/Bgp95 is also expressed on peripheral blood monocytes, dendritic cells, and a … tach-it 6425WebThe ligation of CD180 on B cells by a monoclonal antibody induces activation that leads to upregulation of costimultory molecules, CD80 and CD86, and an increased cell size. CD180 is expressed on mantle zone B cells and marginal zone B cells, but weakly or negative on germinal center B cells. CD180 is also expressed on peripheral blood ... tach2gether